Quake 4 is the fourth game in the series of Quake first-person shooter computer and video games. It was developed by Raven Software and distributed by Activision. Raven Software has collaborated with id Software, the usual developers of Quake games in the past, and for this game, id Software will be supervising the development of the game as well as providing the Doom 3 engine upon which the game is being built. Quake 4 went gold early October 2005 and was released on October 18, 2005 for the PC.

The Quake 4 single player mode continues the story of Quake II pitting the player against a cyborg alien race known as the Strogg. The game follows the story of a marine named Matthew Kane (the first named protagonist in the Quake series) who is a member of a military unit known as Rhino Squad. The marines' mission is to secure the planet Stroggos, homeworld of the Strogg but their ship is shot down and that is when the action begins.